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Lisdexamfetamine

Also known as Vyvanse, Elvanse · Stimulant (amfetamine prodrug)

Withdrawal risk: Lower

What it's used for

  • ADHD
  • Binge-eating disorder (US)

Read about: ADHD, Binge-eating disorder

How it works: Converted to dexamfetamine, which releases dopamine and noradrenaline.

Common side effects

  • Reduced appetite
  • Insomnia
  • Dry mouth
  • Raised heart rate
  • Irritability

Tapering considerations

  • Fatigue, increased sleep and low mood can follow stopping, usually short-lived.
Why smaller steps near the end →

For prescribers & facilitators

  • Controlled drug.
  • Check cardiovascular history before starting.

Sources