Evidence-based deprescribing
Coming off medication, slowly and safely.
Clear, research-linked guidance for people tapering antidepressants and other mental health medications — to share and plan with your prescriber.
Tapering guides
Find your medication
Our focus
Antidepressants, gently.
Withdrawal (discontinuation) effects after stopping antidepressants are common. The largest meta-analysis to date (Henssler et al., 2024) found about 1 in 3 people get symptoms — roughly 1 in 6 more than placebo — and around 1 in 35 have severe symptoms; earlier surveys reported higher rates. Current UK guidance (NICE 2022) recommends slowly reducing the dose in proportionate steps, agreed with your prescriber.
Conditions · three lenses of discovery
Understand the diagnosis behind the prescription — and the meaning beneath it
27 conditions, each explored through three lenses side by side, so you can see the whole picture.
Medical view
The symptoms used to diagnose, by DSM-5-TR and ICD-11, plus common medications.
Alternative theories
Trauma, nervous system, gut–brain, attachment and neurodiversity perspectives.
Spiritual meaning
Buddhist, Ayurvedic, Chinese medicine, Jungian, African, shamanic and Louise Hay views.