What it's used for
- Schizophrenia
- Bipolar mania
- Persistent aggression in dementia or autism (short term)
Read about: Bipolar disorder, Obsessive-compulsive disorder, Autism, Tourette syndrome & tic disorders, Schizophrenia
How it works: Blocks dopamine D2 and serotonin 5-HT2A receptors.
Common side effects
- Raised prolactin
- Movement side effects
- Weight gain
- Sedation
Tapering considerations
- Liquid (1 mg/mL) allows small steps.
For prescribers & facilitators
- Prolactin-related effects are dose-dependent.
Sources
- 01A method for tapering antipsychotic treatment that may minimize the risk of relapse
Horowitz, Jauhar, Natesan, Murray & Taylor, Schizophrenia Bulletin, 2021
- 02The Maudsley Deprescribing Guidelines
Horowitz & Taylor, Wiley-Blackwell, 2024